Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.6
USERS' SCORE
Good
Based on 33 Reviews
8.3
Supplement Facts
Serving Size: 2 Gummies
Amount Per Serving
%DV
Calories
15
Total Carbohydrate
4 g
1%†
Sugar Alcohol
4 g
**
Melatonin
3 mg
**
Passion Flower (Passiflora incarnata) 4:1 extract
4.25 mg
**
Chamomile Flower (Chamomilla recutita) 4:1 extract
4.25 mg
**
Lemon Balm Leaf (Melissa officinalis) 4:1 extract
4 mg
**
Top Medical Research Studies
9.5
Melatonin improves sleep apnea outcomes
We investigated how melatonin affects patients with obstructive sleep apnea and insomnia. In a double-blind trial, thirty patients received either 10 mg of melatonin or a placebo for a month.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
Read More
7
We conducted a study to see if agomelatine, a melatonin-based drug, could help patients with obstructive sleep apnea (OSA). In this randomized and single-blind trial, seventy adults took either agomelatine or a placebo for three nights before sleep testing.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
Read More
7
We explored how melatonin, known for its anti-inflammatory properties, interacts with obstructive sleep apnea (OSA) and related health issues.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
Read More
Most Useful Reviews
9
Improved sleep quality
10 people found this helpful
The Marmalade Miracle has worked wonders for my husband, who suffers from insomnia. He often tumbles around the flat, but these chewable vitamins help him sleep soundly. Just half an hour after taking them, he enters a peaceful slumber.
Read More
10
Calm and deep sleep
2 people found this helpful
This melatonin has replaced the one from Life Extension that caused restless nights. Since switching, my sleep has improved significantly—I now enjoy deep, uninterrupted rest and wake up feeling refreshed. The flavour is fruity yet not too sweet. I take two marmalades half an hour before bed. Highly recommend!
Read More
9
Restful sleep
2 people found this helpful
This melatonin is delicious! I typically have two candies per night. It really works—after taking them, I wake up feeling rested and clear-headed. It's truly beneficial for those who struggle to sleep and users will appreciate the quality and safety of the ingredients.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.6
- All Researches
9.5
Melatonin improves sleep apnea outcomes
We investigated how melatonin affects patients with obstructive sleep apnea and insomnia. In a double-blind trial, thirty patients received either 10 mg of melatonin or a placebo for a month.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
Read More
7
We explored how melatonin, known for its anti-inflammatory properties, interacts with obstructive sleep apnea (OSA) and related health issues.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
Read More
7
We conducted a study to see if agomelatine, a melatonin-based drug, could help patients with obstructive sleep apnea (OSA). In this randomized and single-blind trial, seventy adults took either agomelatine or a placebo for three nights before sleep testing.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
Read More
7
We explored REM sleep behavior disorder (RBD) as a complex condition that can be linked to a variety of underlying disorders. Through a literature review and insights from foundational texts, we recognized that RBD may emerge at any age and can initially appear as an isolated issue or be associated with other significant conditions like Parkinson’s and narcolepsy.
Our findings highlighted that effective management often includes melatonin or clonazepam as treatment options. Furthermore, ongoing research into the connections between RBD and other sleep disorders, such as obstructive sleep apnea, remains vital for enhancing diagnostics and treatment strategies.
Our findings highlighted that effective management often includes melatonin or clonazepam as treatment options. Furthermore, ongoing research into the connections between RBD and other sleep disorders, such as obstructive sleep apnea, remains vital for enhancing diagnostics and treatment strategies.
Read More
User Reviews
USERS' SCORE
Good
Based on 33 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Improved sleep quality
10 people found this helpful
The Marmalade Miracle has worked wonders for my husband, who suffers from insomnia. He often tumbles around the flat, but these chewable vitamins help him sleep soundly. Just half an hour after taking them, he enters a peaceful slumber.
Read More
10
Calm and deep sleep
2 people found this helpful
This melatonin has replaced the one from Life Extension that caused restless nights. Since switching, my sleep has improved significantly—I now enjoy deep, uninterrupted rest and wake up feeling refreshed. The flavour is fruity yet not too sweet. I take two marmalades half an hour before bed. Highly recommend!
Read More
9
Restful sleep
2 people found this helpful
This melatonin is delicious! I typically have two candies per night. It really works—after taking them, I wake up feeling rested and clear-headed. It's truly beneficial for those who struggle to sleep and users will appreciate the quality and safety of the ingredients.
Read More
9
Natural solution
2 people found this helpful
It greatly improves my sleep quality. The flavour is pleasant, and it’s easy to take. This product has been a great help for my severe sleep issues. I purchase it frequently because it contains only natural melatonin, with no side effects or addiction potential. I often need to take 8 pills to experience restful sleep.
Read More
10
Sleep quality improved
This melatonin genuinely helps me sleep soundly. I was initially unsure about the white tea and peach flavour, fearing it might taste artificial, but it's authentic. It’s a lovely treat before bed, and this large bottle is cost-effective compared to local shops. Highly recommend.
Read More
Frequently Asked Questions
7.5
Dream enhancing
4 people found this helpful
I'm thrilled with these cuddly treats. I struggle with falling asleep and often take 1-2 hours to drift off. However, these delightful "sweets" save me, allowing me to have a lovely dream within 15 minutes of consumption. I wholeheartedly recommend them.
7.5
Calm after taking
2 people found this helpful
Very tasty marmalades! It’s unfortunate that only two pieces are recommended, but half an hour after consumption, I enjoy calm, sound sleep, waking up refreshed without any lingering drowsiness.
9
Uninterrupted sleep
1 people found this helpful
I adore that this product comes in gummy form, making it feel less like taking medicine. It works within 30 minutes, providing complete, uninterrupted sleep! Click thumbs up for rewards :)
9
Improved sleep quality
10 people found this helpful
The Marmalade Miracle has worked wonders for my husband, who suffers from insomnia. He often tumbles around the flat, but these chewable vitamins help him sleep soundly. Just half an hour after taking them, he enters a peaceful slumber.
10
Calm and deep sleep
2 people found this helpful
This melatonin has replaced the one from Life Extension that caused restless nights. Since switching, my sleep has improved significantly—I now enjoy deep, uninterrupted rest and wake up feeling refreshed. The flavour is fruity yet not too sweet. I take two marmalades half an hour before bed. Highly recommend!
7.5
Feeling refreshed
2 people found this helpful
I've repurchased this product and introduced it to my boyfriend. With life being so stressful, one pill before bed does the trick for me. Within 15 minutes, I feel the effects and wake up refreshed the next day. The white tea and peach flavour is delightful and not overly sugary.
9.5
Melatonin improves sleep apnea outcomes
We investigated how melatonin affects patients with obstructive sleep apnea and insomnia. In a double-blind trial, thirty patients received either 10 mg of melatonin or a placebo for a month.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
7
We explored how melatonin, known for its anti-inflammatory properties, interacts with obstructive sleep apnea (OSA) and related health issues.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
7
We conducted a study to see if agomelatine, a melatonin-based drug, could help patients with obstructive sleep apnea (OSA). In this randomized and single-blind trial, seventy adults took either agomelatine or a placebo for three nights before sleep testing.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
References
- Wei Z, Shen H, Wang F, Huang W, Li X, et al. Melatonin mediates intestinal barrier dysfunction and systemic inflammation in moderate-severe OSA patients. Ann Med. 2024;56:2361825. doi:10.1080/07853890.2024.2361825
- Motlaq TM, Rahimi B, Amini S. Effect of melatonin on insomnia and daytime sleepiness, in patients with obstructive sleep apnea and insomnia (COMISA): A randomized double-blinded placebo-controlled trial. J Pharm Health Care Sci. 2024;10:25. doi:10.1186/s40780-024-00347-9
- Dastan F, Gholizadeh Niari B, Adimi Naghan P, Barati S, Eskandari R. Evaluating the Effects of Agomelatine on Polysomnography Parameters in Patients with Obstructive Sleep Apnea. J Pharm Pharm Sci. 2023;25:418. doi:10.18433/jpps33252
- Schenck CH. REM sleep behavior disorder as a complex condition with heterogeneous underlying disorders: clinical management and prognostic implications [Commentary]. Sleep Breath. 2022;26:1289. doi:10.1007/s11325-022-02574-6
